Age-related inflammation and insulin resistance: a review of their intricate interdependency

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Age-related inflammation and insulin resistance: a review of their intricate interdependency

Chronic inflammation is a major risk factor underlying aging and the associated diseases of aging; of particular interest is insulin resistance during aging. Chronic inflammation impairs normal lipid accumulation, adipose tissue function, mitochondrial function, and causes endoplasmic reticulum (ER) stress, which lead to insulin resistance. However, some studies show that insulin resistance its...

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ژورنال

عنوان ژورنال: Archives of Pharmacal Research

سال: 2014

ISSN: 0253-6269,1976-3786

DOI: 10.1007/s12272-014-0474-6